Work package 4
Compounds from WP1, WP2, WP3 will be further analysed by groups oriented to
characterization and validation of PKs as drug targets, especially as
regards structural and functional studies. These laboratories will give the
feedback of bio-activity to the screening/synthesis laboratories (WP1, WP2,
WP3).
It is essential to get the feedback information from biological tests as
soon as possible, and therefore the bioactivity testing should be done
parallel to the synthesis work.
Synthesis of pure chemicals takes a relatively long period of time as
compared to make tests. New bioactivity tests will be developed and this
development also requires long time. These are done in parallel.
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